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Apr232012

Reserverlogix (RVX.CN) : Announces Mechanism of Action for RVX-208

DDE Editor

RVX.CN announced that RVX-208 increases apolipoprotein A-I (ApoA-I) production and that its data shows RVX-208 to be an inhibitor of the Bromodomain and Extraterminal Domain (BET) proteins.
RVX-208 acts on BET proteins, including BRD4, a member of the BET-protein family, leading to increased transcription of the ApoA-I gene followed by production of more ApoA-I protein.
Clinical benefits of RVX-208 are currently being explored in two concurrent Phase 2B clinical trials (SUSTAIN and ASSURE), led by Cleveland Clinic.
As previously announced, Conference Call and Webcast today at 11ET: 800.319.4610 or 604.638.5340

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